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  • Evolution, Composition and Regulation of Supernumerary B Chromosomes
    Evolution, Composition and Regulation of Supernumerary B Chromosomes

    Supernumerary B chromosomes (Bs) are dispensable genetic elements found in thousands of species of plants and animals, and some fungi. Since their discovery more than a century ago, they have been a source of puzzlement, as they only occur in some members of a population and are absent from others. When they do occur, they are often harmful, and in the absence of “selfishness”, based on mechanisms of mitotic and meiotic drive, there appears to be no obvious reason for their existence. Cytogeneticists have long wrestled with questions about the biological existence of these enigmatic elements, including their lack of any adaptive properties, apparent absence of functional genes, their origin, sequence organization, and co-evolution as nuclear parasites. Emerging new technologies are now enabling researchers to step up a gear, to look enthusiastically beyond the previous limits of the horizon, and to uncover the secrets of these “silent” chromosomes. This book provides a comprehensive guide to theoretical advancements in the field of B chromosome research in both animal and plant systems. 

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  • Abnormal Chromosomes : The Past, Present, and Future of Cancer Cytogenetics
    Abnormal Chromosomes : The Past, Present, and Future of Cancer Cytogenetics

    Explore the past, present, and future of cancer cytogeneticsIn Abnormal Chromosomes: The Past, Present, and Future of Cancer Cytogenetics, globally renowned researchers Drs.Sverre Heim and Felix Mitelman deliver a state-of-the-art review of how cancer cytogenetic analyses have contributed to an improved understanding of tumorigenesis as well as to the diagnosis and treatment of cancer patients.The book also discusses how cytogenetics – the study of chromosomes - meets, interacts with, and cross-fertilizes other investigative technologies, including molecular somatic cell genetics. The book provides an impetus to think more deeply about the role chromosomes, and their abnormalities, play in health and disease, especially in neoplastic disorders.From which origins did cytogenetics develop? How did the finding of acquired chromosomal abnormalities in cells of leukemias and solid tumors influence our understanding of cancer as a biological process?How was information of this nature put to good use in the clinical management of cancer patients?Abnormal Chromosomes: The Past, Present, and Future of Cancer Cytogenetics offers readers: A thorough introduction to ancient theories of disease, the advent of cellular pathology, and how a scientific interest in chromosomes developedComprehensive exploration of the conceptual importance of Theodor Boveri and his somatic mutation theory of cancerA detailed chronological resume of cancer cytogenetic discoveries during the 20th centuryIn-depth discussions of the role of chromosome abnormalities, oncogenes, and tumor suppressor genes in leukemias, lymphomas, and solid tumors, together with a survey of what chromosome analyses have revealed about the clonal evolution of neoplastic cell populationsA discussion of the importance of pathogenetic classifications of neoplastic diseases, the role chromosome abnormalities play in this context, and which technological breakthroughs can be expected in chromosome-oriented cancer research Abnormal Chromosomes: The Past, Present, and Future of Cancer Cytogenetics was written for everyone with a scientific or clinical interest in cancer, especially how acquired chromosome abnormalities lead to neoplastic transformation.The book teaches how cytogenetic analyses contribute to a better understanding of tumorigenesis, but also how the finding of specific chromosome aberrations can be crucial for the diagnosis, prognosis, and management of cancer patients.

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  • Streaming Music, Streaming Capital
    Streaming Music, Streaming Capital

    In Streaming Music, Streaming Capital, Eric Drott analyzes the political economy of online music streaming platforms.Attentive to the way streaming has reordered the production, circulation, and consumption of music, Drott examines key features of this new musical economy, including the roles played by data collection, playlisting, new methods of copyright enforcement, and the calculation of listening metrics.Yet because streaming underscores how uneasily music sits within existing regimes of private property, its rise calls for a broader reconsideration of music’s complex and contradictory relation to capitalism.Drott's analysis is not simply a matter of how music is formatted in line with dominant measures of economic value; equally important is how music eludes such measures, a situation that threatens to reduce music to a cheap, abundant resource.By interrogating the tensions between streaming’s benefits and pitfalls, Drott sheds light on music’s situation within digital capitalism, from growing concentrations of monopoly power and music’s use in corporate surveillance to issues of musical value, labor, and artist pay.

    Price: 25.99 £ | Shipping*: 3.99 £
  • Music in Orbit : Satellite Radio in the Streaming Space Age
    Music in Orbit : Satellite Radio in the Streaming Space Age

    Years before the advent of music streaming, Sirius and XM established satellite radio services that attracted paying subscribers through their ever-expanding lineup of niche music channels and exclusive celebrity-hosted programming.Music in Orbit is the first book to explore how satellite radio bridges legacy broadcast music radio and streaming platforms, serving as both precursor and integral player in today's streaming media environment.Arguing for the ongoing significance of radio in the digital age and the pernicious effects of monopoly power on the vibrancy of contemporary music industries, Music in Orbit offers essential context for the serious problems now facing working musicians, music consumers, and music communities.

    Price: 25.00 £ | Shipping*: 3.99 £
  • Are a chromatid chromosome and two chromatid chromosomes homologous chromosomes or a set of chromosomes?

    A chromatid chromosome and two chromatid chromosomes are not homologous chromosomes, but rather a set of chromosomes. Homologous chromosomes are pairs of chromosomes that contain the same genes in the same order, one from each parent. In contrast, chromatid chromosomes are duplicated copies of a single chromosome that are joined together at the centromere. Two chromatid chromosomes refer to a duplicated chromosome in preparation for cell division.

  • Are chromosomes unreliable?

    Chromosomes are not inherently unreliable, as they are the structures that carry our genetic information and play a crucial role in cell division and inheritance. However, errors can occur during the process of chromosome replication and segregation, leading to genetic mutations and disorders. Additionally, environmental factors and lifestyle choices can also impact the stability and integrity of chromosomes. Overall, while chromosomes are essential for the functioning of our cells and the inheritance of genetic traits, they are not immune to errors and can be influenced by various factors.

  • What is the difference between single chromosomes and double chromosomes?

    Single chromosomes refer to a single strand of DNA that contains genetic information. In contrast, double chromosomes refer to a pair of identical chromosomes, one from each parent, that are joined together at the centromere. Single chromosomes are found in haploid cells, such as gametes, while double chromosomes are found in diploid cells, such as somatic cells. Double chromosomes allow for genetic diversity and the exchange of genetic material through processes such as meiosis and fertilization.

  • What is the difference between chromosomes, chromatids, and double chromosomes?

    Chromosomes are the structures within cells that contain genetic information. They are made up of DNA and proteins. Chromatids are the two identical copies of a chromosome that are formed during the process of DNA replication. Double chromosomes, on the other hand, refer to the paired chromosomes that are formed during cell division, with each chromosome consisting of two sister chromatids. In summary, chromosomes are the overall structures containing genetic material, chromatids are the individual copies of a chromosome, and double chromosomes are the paired chromosomes formed during cell division.

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  • Genetics 101 : From Chromosomes and the Double Helix to Cloning and DNA Tests, Everything You Need to Know about Genes
    Genetics 101 : From Chromosomes and the Double Helix to Cloning and DNA Tests, Everything You Need to Know about Genes

    A clear and straightforward explanation of genetics in this new edition of the popular 101 series.Our genetic makeup determines so much about who we are, and what we pass on to our children—from eye color, to height, to health, and even our longevity.Genetics 101 breaks down the science of how genes are inherited and passed from parents to offspring, what DNA is and how it works, how your DNA affects your health, and how you can use your personal genomics to find out more about who you are and where you come from. Whether you’re looking for a better scientific understanding of genetics, or looking into your own DNA, Genetics 101 is your go-to source to discover more about both yourself and your ancestry.

    Price: 12.99 £ | Shipping*: 3.99 £
  • Music Charli XCX Brat Album Keychains Hot Songs Playlist Pendant Keyring for Accessories Bag Key
    Music Charli XCX Brat Album Keychains Hot Songs Playlist Pendant Keyring for Accessories Bag Key

    Music Charli XCX Brat Album Keychains Hot Songs Playlist Pendant Keyring for Accessories Bag Key

    Price: 1.14 £ | Shipping*: 1.99 £
  • Before Streaming Music
    Before Streaming Music

    Travel back in time to find out what life was like before streaming music.Historical photographs, helpful infographics, and a “Blast from the Past” special feature provide readers an engaging overview of records, cassette tapes, and other ways people listened to their favorite tunes.

    Price: 10.99 £ | Shipping*: 3.99 £
  • Pandemic Playlist : An Exploration of COVID-Inspired Popular Music
    Pandemic Playlist : An Exploration of COVID-Inspired Popular Music

    Pandemic Playlist: An Exploration of COVID-inspired Popular Music takes readers back to 2020, when the COVID-19 pandemic wreaked havoc on the music industry.Focusing on those artists who responded directly to the pandemic with their music, Kevin Farrell explores a selection of songs written and recorded about COVID-19.These songs range from the hilariously tongue-in-cheek to the painfully earnest to the self-righteously angry, coming from musicians obscure, world famous, and up-and-coming.Farrell argues that these songs, both originals and repurposed covers, are best classified by rhetorical approach, rather than musical style, identifying four basic categories of COVID-inspired popular music: the Coronavirus Anthem (Bono’s “Let Your Love Be Known,” Alicia Keys’ “Good Job”), Pandemic Pop (Cardi B and iMarkkeyz’s “Coronavirus,” Curtis Roach and Tyga’s “Bored in the House”), the COVID Cover (Gal Gadot’s “Imagine,” Juvenile’s “Vax That Thang Up”), and Pandemic Protest (Ian Brown’s “Little Seed Big Tree,” Kid Rock’s “We The People”).Through a study of these songs, and many more, this book seeks to understand what the pandemic and the music it inspired can teach us about the previously unimaginable.

    Price: 81.00 £ | Shipping*: 0.00 £
  • Does a homologous pair of chromosomes consist of two single-chromatid chromosomes or two double-chromatid chromosomes?

    A homologous pair of chromosomes consists of two single-chromatid chromosomes. Each chromosome in the pair comes from one parent, and they carry the same genes in the same order, but may have different versions of those genes. During the S phase of the cell cycle, each single-chromatid chromosome replicates to form a double-chromatid chromosome, but these double-chromatid chromosomes do not pair up with each other during normal cell division.

  • What is the difference between chromatids, chromosomes, and pairs of chromosomes?

    Chromatids are two identical copies of a chromosome that are joined together at the centromere. Chromosomes are thread-like structures made of DNA and proteins that contain genetic information. Pairs of chromosomes refer to two homologous chromosomes, one inherited from each parent, that carry similar genes but may have different variations. In summary, chromatids are the duplicated copies of a single chromosome, chromosomes are the structures that contain genetic material, and pairs of chromosomes are homologous chromosomes inherited from each parent.

  • What is the difference between double chromosomes and homologous double chromosomes?

    Double chromosomes refer to a pair of identical chromosomes that are present in a diploid organism, one inherited from each parent. On the other hand, homologous double chromosomes are a pair of chromosomes that are similar in size, shape, and genetic content, but not identical. Homologous chromosomes carry the same genes in the same order, but may have different versions of those genes (alleles) due to genetic variation.

  • How do chromosomes spiralize?

    Chromosomes spiralize through a process called supercoiling. This occurs when the DNA double helix is twisted around itself, creating a more compact structure. Enzymes called topoisomerases are responsible for this process, helping to regulate the level of supercoiling in the chromosome. Supercoiling allows the long DNA molecule to be packaged into the small space of the cell nucleus, and also plays a role in regulating gene expression and DNA replication.

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